Paxil

Generic Name: Paroxetine (pa ROCK sah teen)
Brand Names: Paxil, Paxil CR, Pexeva

What is the most important information I should know about Paxil?

• While you are taking Paxil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Paxil. In patients younger than 18 years, the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Paxil. Do not stop taking Paxil.

• Do not stop taking Paxil without first talking to your doctor. It may take 4 weeks or more for you to start feeling better and unpleasant side effects may be experienced if you stop taking Paxil suddenly.

What is Paxil?

• Paxil is in a class of drugs called selective serotonin reuptake inhibitors. Paxil affects chemicals in the brain that may become unbalanced and cause depression, panic or anxiety, or obsessive or compulsive symptoms.

• Paxil is used to treat depression, obsessive-compulsive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder (social phobia), posttraumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

• Paxil may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Paxil?

• While you are taking Paxil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Paxil. In patients younger than 18 years, the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Paxil. Do not stop taking Paxil.

• Do not take Paxil if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred when these medicines have been used together. Also, do not take Paxil if you are taking thioridazine (Mellaril). Dangerous, even fatal irregular heartbeats may occur if these medicines are taken together. You must wait 5 weeks after stopping Paxil before taking thioridazine (Mellaril).

• You may not be able to take Paxil, or you may need a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

• Paxil is in the FDA pregnancy category C. Babies exposed to Paxil and/ or other drugs of the same class during the third trimester of pregnancy may develop medical complications. Discuss the risks with your doctor. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

• Paxil passes into breast milk and may affect a nursing baby. Do not take Paxil without first talking to your doctor if you are breast-feeding a baby.

How should I take Paxil?

• Take Paxil exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

• Take each dose with water.

• Swallow the controlled-release tablets (Paxil CR) whole, without crushing or chewing. They are specially formulated to release the medication slowly in the body.

• Shake the suspension well before measuring a dose. To ensure that you get the correct dose, measure the suspension with a dose-measuring cup or spoon, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

• Paxil may be taken with or without food.

• Try to take Paxil at the same time each day.

• Do not stop taking Paxil without first talking to your doctor. It may take 4 weeks or more for you to start feeling better and unpleasant side effects may be experienced if you stop taking Paxil suddenly.

• Store Paxil at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.

• Symptoms of a Paxil overdose include nausea, vomiting, tremor, seizures, agitation, drowsiness, hyperactivity, and enlarged pupils.

What should I avoid while taking Paxil?

• Use caution when driving, operating machinery, or performing other hazardous activities. Paxil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

• Use alcohol cautiously. Alcohol may increase drowsiness or dizziness while taking Paxil.

What other drugs will affect Paxil?

• Do not take Paxil if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred when these medicines have been used together. Also, do not take Paxil if you are taking thioridazine (Mellaril). Dangerous, even fatal irregular heartbeats may occur if these medicines are taken together. You must wait 5 weeks after stopping Paxil before taking thioridazine (Mellaril).

• You may not be able to take Paxil, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

• Drugs other than those listed here may also interact with Paxil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Useful Resources • Canadian Pharmacies • Consultations • Diet Supplements • Drugs Business • Fitness • Hair Care • Health • Health Resources • Herbal Products • Medication • Online Pharmacies • Others • Pain Relief • Pharmaceuticals • Pharmacies • Sexual Health • Vitamins